Gene: [05^/HARS] histidyl-tRNA synthetase;


FUN

[1] Systematic name: L-histidine:tRNA(His) ligase (AMP-forming).
[2] Catalyzes reaction: ATP + L-histidine + tRNA(His) = = AMP + pyrophosphate + L-histidyl-tRNA(Val)."

FAG

[1] Several genes coding for various aminoacyl-tRNA synthetases are mapped to Chr 5, see GEM:05p1/TARS.
[2] About histidyl-tRNA synthetase related gene oriented head-to-head with respect to HARS see GEM:05^/HARSR."

REF

PRO,LOC "Carlock LR &: AJHG, 37, 839-852, 1985a
PRO,LOC "Carlock LR &: CCG, 40, 598, 1985b
CLO,SEQ "O'Hanlon TP &: BBRC, 210, N2, 556-566, 1995
CLO,SEQ "Raben N &: NAR, 20, 1075-1081, 1992
PRO,LOC "Tsui FWL &: Mol Cell Biol, 5, 2381-2388, 1985
CLO,SEQ "Tsui HW &: Gene, 131, 201-208, 1993
PRO,LOC "Wasmuth JJ, Carlock LR: Somat Cell Mol Genet, 12, 513-517, 1986

SWI

 SWISSPROT: P12081

KEY

trl, aac

CLA

coding, basic

LOC

05

MIM

 MIM: 142810

EZN

 ENZYME: 6.1.1.21